University of California, Davis, Center for Neuroscience, and California National Primate Research Center, Davis, CA
The dataset includes anatomical, diffusion, and fMRI data from 19 macaques.
Usage Agreement
Creative Commons – Attribution-NonCommercial Share Alike (CC-BY-NC-SA)- Standard INDI data sharing policy. Prohibits use of the data for commercial purposes.
Species
Macaca mulatta
Scanner Specifications
- Siemens Skyra 3T
- 4-channel clamshell coil
Sample Description
- Sample size: 19
- Age distribution: 18.5-22.5 years
- Weight distribution: 7.28-14.95kg
- Sex distribution: all female
Click here for the full sample description (.csv)
Scan Procedures and Parameters
Ethics approval: UC-Davis IACUC
Animal care and housing: CNPRC is staffed with 7 full-time veterinarians and an extensive staff of veterinary and husbandry technicians. Monkeys were housed in pairs (N=16) or singly (N=4) indoors in standard primate caging, in housing rooms containing other rhesus monkeys. Single-housed monkeys had failed repeated attempts to find compatible cage mates from elsewhere in the colony. All monkeys received environmental enrichment consisting of toys and novel food items.
Any applicable training: none prior to MRI scanning
Click here for scan parameters(.txt).
Scanning preparations
Anesthesia procedures: ketamine, dexmedetomidine, buprenorphine prior to intubation and placement in stereotaxic frame; isoflurane maintenance anesthesia (1-2%, to effect)
Time between anesthesia and scanning: Monkeys were placed in the scanner as soon as isoflurane anesthesia was initiated and stable
Head fixation: Monkeys were placed in an MRI-compatible stereotaxic frame (Kopf)
Position in scanner and procedure used: Sphinx position head first (recorded as head first prone in scanner; note that header info have been corrected to reflect anatomy)
Contrast agent: none
During scanning
Physiological monitoring: pulse rate, SpO2, end tidal CO2, inspired/expired isoflurane, blood pressure
Additional procedures: artificial ventilation to maintain normocapnia, normothermia maintained by heated air blanket
Scan sequences
- Resting-state:
- Voxel resolution: 1.4 x 1.4 x 1.4 mm
- TE: 24ms
- TR: 1600ms
- FOV = 140mm
- Gradient echo image included
- Diffusion-weighted:
- Voxel resolution: 1.4 x 1.4 x 1.4 mm
- TE: 115ms
- TR: 6400ms
- Slice gap: 1.4mm
- b-values: 1600s/mm2, 800s/mm2
- Structural:
- T1
- Voxel resolution: 0.3 x 0.3 x 0.3 mm
- TE: 3.65ms
- TR: 2500ms
- TI: 1100ms
- Flip angle: 7°
- T2
- Voxel resolution: 0.3 x 0.3 x 0.3 mm
- TE: 307ms
- TR: 3000ms
Personnel
- Mark G. Baxter, PhD1
- Paula L. Croxson, DPhil1
- John H. Morrison, PhD2
1Department of Neuroscience, Mount Sinai School of Medicine, New York, NY
2California National Primate Research Center, and Department of Neurology, University of California, Davis School of Medicine
Acknowledgements
We thank Mary Roberts, Deborah Kent, Lisa Novik, Michael Buonocore (deceased) for their support.
Funding
This data repository was supported by NIA P01-AG016765.
Downloads
Click here to download the data. Users will first be prompted to log on to NITRC and will need to register with the 1000 Functional Connectomes Project website on NITRC to gain access to the PRIME-DE datasets.